The future implant material for bone regeneration.
Sometimes to take a major step forward, you have to completely change direction.
Given the world’s demographic shift towards an older population and today’s lifestyles with more and more sportive activity, an inevitable rise of orthopedic injuries and diseases is expected.
Today, most of the surgical operations to repair fractures and bone defects are performed using autografts and allografts despite their limitations in terms of availability, donor-site morbidity and potential negative immune responses. This has triggered research to find fully synthetic alternative bone substitute materials.
The invention of bonewool active® relates to the preparation of a new and advanced implant material consisting of a biodegradable polymer such as a PLGA with up to 40wt% of amorphous tricalcium phosphate (ATCP) nanoparticles incorporated into the polymer. These ATCP nanoparticles can be solely prepared by a dry, one step preparation method, so called flame spray synthesis. The new composite is prepared by electrospinning, a technique, which produces open structured, ultrafine fibers. The resulting product is very flexible and easy to shape due to its cotton wool-like appearance.
Main advantages of bonewool active® compared to other commercially available Products:
• Easy to apply: flexible, elastic, compressible
• Fully synthetic
• Excellent bioactivity
• Apatite deposition after 48 hours
• Easily removable if misplaced
• Combinable with other products such as growth factors or other particles
• Possible incorporation of antibacterial nanoparticles (e.g. silver)
The preeminent technical specs combined with a superior experience in handling, bonewool active® will set new benchmarks in the field of implant materials for bone regeneration.
There will be bonewool active®. And then there will be everything else.